Network Activity of Fear

Oscillatory network rhythms are critical means for the interregional communication in the brain; they control information transfer, information filtering and synaptic plasticity in different behavioral states. In the hippocampus, two types of rhythms, gamma oscillations and sharp-wave ripples are generated, depending on the the level of cholinergic activation. We have identified molecular and cellular mechanisms that control the generation and propagation of these rhythms and their modulation by fear and anxiety.



Çalışkan G, Stork O. A Hippocampal network oscillations at the interplay between innate anxiety and learned fear. Psychopharmacology (Berl). 2019; 236(1):321-338

Çalışkan G, Stork O. Hippocampal network oscillations as mediators of behavioural metaplasticity: insights from emotional learning. Neurobiol Learn Mem. 2018; 154:37-53.

Çalışkan G, Müller I, Semtner M, Winkelmann A, Raza AS, Hollnagel JO, Rösler A, Heinemann U, Stork O, Meier JC. Identification of Parvalbumin Interneurons as Cellular Substrate of Fear Memory Persistence. Cereb Cortex. 2016 May;26(5):2325-40.

Caliskan, G., Albrecht, A., Hollnagel, J. O., Rosler, A., Richter-Levin, G., Heinemann, U., & Stork, O. (2015). Long-term changes in the CA3 associative network of fear-conditioned mice. Stress (Amsterdam, Netherlands), 1–32. doi:10.3109/10253890.2015.1004628



Collaborative Research Center 779, project B05: GABA interneurons as mediators of cognitive flexibility 

PI: Prof. Dr. Oliver Stork

Postdoc: Dr. Ahsan Raza



CBBS Science Campus, project group 6

PIs: Dr. Gürsel Çalişkan, Prof. Dr. Oliver Stork

  Researcher: Sara Enrile



ESF graduate school ABINEP, project 2-5 Modulation of behaviorally relevant oscillations through interneuron networks


PIs: Prof. Dr. Oliver Stork, Dr. Thomas Munsch (Institute of Physiology)

Graduate Student: Dr. Evangelia Pollali  

Associated Researcher: Dr. Gürsel Çalişkan