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Publications

2017

Raza SA, Albrecht A, Çalışkan G, Müller B, Demiray YE, Ludewig S, Meis S, Faber N, Hartig R, Schraven B, Lessmann V, Schwegler H, Stork O. HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience. Nat Commun. 2017 Aug; 8(1):189.

Albrecht A, Stork O. Circadian Rhythms in Fear Conditioning: An Overview of Behavioral, Brain System, and Molecular Interactions. Neural Plast. 2017, 3750307.

Castro H, Kul E, Buijsen RAM, Severijnen LWFM, Willemsen R, Hukema RK, Stork O, Santos M. Selective rescue of heightened anxiety but not gait ataxia in a premutation 90CGG mouse model of Fragile X-associated tremor/ataxia syndrome. Hum Mol Genet. 2017 Jun ;26(11):2133-2145.

Altmüller F, Pothula S, Annamneedi A, Nakhaei-Rad S, Montenegro-Venegas C, Pina-Fernández E, Marini C, Santos M, Schanze D, Montag D, Ahmadian MR, Stork O, Zenker M, Fejtova A. Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy. PLoS Genet. 2017 Mar;13(3):e1006684. Correction: 2017 Jun;13(6):e1006843.

Albrecht A, Müller I, Ardi Z, Çalışkan G, Gruber D, Ivens S, Segal M, Behr J, Heinemann U, Stork O, Richter-Levin G. Neurobiological consequences of juvenile stress: A GABAergic perspective on risk and resilience. Neurosci Biobehav Rev. 2017 Mar;74(Pt A):21-43.

Tuchen M, Wilisch-Neumann A, Daniel EA, Baldauf L, Pachow D, Scholz J, Angenstein F, Stork O, Kirches E, Mawrin C. Receptor tyrosine kinase inhibition by regorafenib/sorafenib inhibits growth and invasion of meningioma cells. Eur J Cancer. 2017 Mar;73:9-21.

2016

Thiere M, Kliche S, Müller B, Teuber J, Nold I, Stork O. Integrin Activation Through the Hematopoietic Adapter Molecule ADAP Regulates Dendritic Development of Hippocampal Neurons. Front. Mol. Neurosci. 2016 Sep; 9:91.

Albrecht A, Ivens S, Papageorgiou IE, Çalışkan G, Saiepour N, Brück W, Richter-Levin G, Heinemann U, Stork O. Shifts in excitatory/inhibitory balance by juvenile stress: A role for neuron-astrocyte interaction in the dentate gyrus. Glia. 2016 Jun;64(6):911-22.

Çalışkan G, Müller I, Semtner M, Winkelmann A, Raza AS, Hollnagel JO, Rösler A, Heinemann U, Stork O, Meier JC. Identification of Parvalbumin Interneurons as Cellular Substrate of Fear Memory Persistence. Cereb Cortex. 2016 May;26(5):2325-40.

Spilker C, Nullmeier S, Grochowska KM, Schumacher A, Butnaru I, Macharadze T, Gomes GM, Yuanxiang P, Bayraktar G, Rodenstein C, Geiseler C, Kolodziej A, Lopez-Rojas J, Montag D, Angenstein F, Bär J, D’Hanis W, Roskoden T, Mikhaylova M, Budinger E, Ohl FW, Stork O, Zenclussen AC, Karpova A, Schwegler H, Kreutz MR. A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis. PLoS Genet. 2016 Mar 15;12(3):e1005907.

Šmidák R, Mayer RL, Bileck A, Gerner C, Mechtcheriakova D, Stork O, Lubec G, Li L. Quantitative proteomics reveals protein kinases and phosphatases in the individual phases of contextual fear conditioning in the C57BL/6J mouse. Behav Brain Res 2016 Apr 15;303:208-17. doi: 10.1016/j.bbr.2015.12.033.

2015

Melzer, N., Budde, T., Stork, O., Meuth, S.G. Limbic Encephalitis: Potential Impact of Adaptive Autoimmune Inflammation on Neuronal Circuits of the Amygdala. Front Neurol. 2015 Aug 3;6:171. doi:10.3389/fneur.2015.00171.

Lübkemann, R., Eberhardt, J., Röhl, F.W., Janitzky, K., Nullmeier, S., Stork, O., Schwegler, H., Linke, R. Identification and Characterization of GABAergic Projection Neurons from Ventral Hippocampus to Amygdala. Brain Sci, 2015 Jul 31;5(3):299-317. doi:10.3390/brainsci5030299.

Sase S, Sase A, Sialana FJ Jr, Gröger M, Bennett KL, Stork O, Lubec G, Li L. Individual phases of contextual fear conditioning differentially modulate dorsal and ventral hippocampal GluA1-3, GluN1-containing receptor complexes and subunits. Hippocampus, 2015 Apr 25. doi:10.1002/hipo.22470

Bangel, F. N., Yamada, K., Arai, M., Iwayama, Y., Balan, S., Toyota, T., Iwata Y., Suzuki, K., Kikuchi, M., Hashimoto, T., Kanahara, N., Mori, N., Itokawa, M., Stork, O., Yoshikawa, T. (2015). Genetic analysis of the glyoxalase system in schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 59, 105-110. doi:10.1016/j.pnpbp.2015.01.014

Sandhu, K. V., Yanagawa, Y., & Stork, O. (2015). Transcriptional regulation of glutamic acid decarboxylase in the male mouse amygdala by dietary phyto‐oestrogens. Journal of Neuroendocrinology, 27(4), 285-292. doi: 10.1111/jne.12262

Sharvit, A., Segal, M., Kehat, O., Stork, O., & Richter-Levin, G. (2015). Differential modulation of synaptic plasticity and local circuit activity in the dentate gyrus and CA1 regions of the rat hippocampus by corticosterone. Stress, (0), 1-9. doi: 10.3109/10253890.2015.1023789

Perna, J. C., Wotjak, C. T., Stork, O., & Engelmann, M. (2015). Timing of presentation and nature of stimuli determine retroactive interference with social recognition memory in mice. Physiology and Behavior, 143, 10-14. doi:10.1016/j.physbeh.2015.02.029

Gruber, D., Gilling, K. E., Albrecht, A., Bartsch, J. C., Çalışkan, G., Richter-Levin, G., Stork, O., Heinemann, U., Behr, J. (2015). 5-HT receptor-mediated modulation of granule cell inhibition after juvenile stress recovers after a second exposure to adult stress. Neuroscience. doi:10.1016/j.neuroscience.2015.02.050

Caliskan, G., Albrecht, A., Hollnagel, J. O., Rosler, A., Richter-Levin, G., Heinemann, U., & Stork, O. (2015). Long-term changes in the CA3 associative network of fear-conditioned mice. Stress (Amsterdam, Netherlands), 1–32. doi:10.3109/10253890.2015.1004628

Mucic, G., Sase, S., Stork, O., Lubec, G., & Li, L. (2015). Networks of protein kinases and phosphatases in the individual phases of contextual fear conditioning in the C57BL/6J mouse. Behavioural Brain Research, 280, 45–50. doi:10.1016/j.bbr.2014.11.024

2014

Bergado-Acosta, J. R., Muller, I., Richter-Levin, G., & Stork, O. (2014). The GABA-synthetic enzyme GAD65 controls circadian activation of conditioned fear pathways. Behavioural Brain Research, 260, 92–100. doi:10.1016/j.bbr.2013.11.042

Brandewiede, J., Stork, O., & Schachner, M. (2014). NCAM deficiency in the mouse forebrain impairs innate and learned avoidance behaviours. Genes, Brain, and Behavior. doi:10.1111/gbb.12138

Hadad-Ophir, O., Albrecht, A., Stork, O., & Richter-Levin, G. (2014). Amygdala activation and GABAergic gene expression in hippocampal sub-regions at the interplay of stress and spatial learning. Frontiers in Behavioral Neuroscience, 8, 3. doi:10.3389/fnbeh.2014.00003

Li, L., You, L., Sunyer, B., Patil, S., Hoger, H., Pollak, A., Stork, O., Lubec, G. (2014). Hippocampal protein kinase C family members in spatial memory retrieval in the mouse. Behavioural Brain Research, 258, 202–207. doi:10.1016/j.bbr.2013.09.039

Muller, I., Caliskan, G., & Stork, O. (2014). The GAD65 knock out mouse – a model for GABAergic processes in fear- and stress-induced psychopathology. Genes, Brain, and Behavior. doi:10.1111/gbb.12188

Muller, I., Obata, K., Richter-Levin, G., & Stork, O. (2014). GAD65 haplodeficiency conveys resilience in animal models of stress-induced psychopathology. Frontiers in Behavioral Neuroscience, 8, 265. doi:10.3389/fnbeh.2014.00265

Rehberg, K., Kliche, S., Madencioglu, D. A., Thiere, M., Muller, B., Meineke, B. M., Freund, C., Budinger, E., Stork, O. (2014). The serine/threonine kinase Ndr2 controls integrin trafficking and integrin-dependent neurite growth. The Journal of Neuroscience, 34(15), 5342–5354. doi:10.1523/JNEUROSCI.2728-13.2014

Sandhu, K. V, Lang, D., Muller, B., Nullmeier, S., Yanagawa, Y., Schwegler, H., & Stork, O. (2014). Glutamic acid decarboxylase 67 haplodeficiency impairs social behavior in mice. Genes, Brain, and Behavior, 13(4), 439–450. doi:10.1111/gbb.12131

Sase, S., Stork, O., Lubec, G., & Li, L. (2014). Contextual fear conditioning modulates hippocampal AMPA-, GluN1- and serotonin receptor 5-HT1-containing receptor complexes. Behavioural Brain Research, 278C, 44–54. doi:10.1016/j.bbr.2014.09.035

2013

Albrecht, A., Caliskan, G., Oitzl, M. S., Heinemann, U., & Stork, O. (2013). Long-lasting increase of corticosterone after fear memory reactivation: anxiolytic effects and network activity modulation in the ventral hippocampus. Neuropsychopharmacology, 38(3), 386–394. doi:10.1038/npp.2012.192

Albrecht, A., Thiere, M., Bergado-Acosta, J. R., Poranzke, J., Muller, B., & Stork, O. (2013). Circadian modulation of anxiety: a role for somatostatin in the amygdala. PloS One, 8(12), e84668. doi:10.1371/journal.pone.0084668

Brandewiede, J., Jakovcevski, M., Stork, O., & Schachner, M. (2013). Role of stress system disturbance and enhanced novelty response in spatial learning of NCAM-deficient mice. Stress (Amsterdam, Netherlands), 16(6), 638–646. doi:10.3109/10253890.2013.840773

Li, L., Sase, A., Patil, S., Sunyer, B., Hoger, H., Smalla, K.-H., Stork, O., Lubec, G. (2013). Distinct set of kinases induced after retrieval of spatial memory discriminate memory modulation processes in the mouse hippocampus. Hippocampus, 23(8), 672–683. doi:10.1002/hipo.22127

Pachow, D., Andrae, N., Kliese, N., Angenstein, F., Stork, O., Wilisch-Neumann, A., Kirches, E., Mawrin, C. (2013). mTORC1 inhibitors suppress meningioma growth in mouse models. Clinical Cancer Research, 19(5), 1180–1189. doi:10.1158/1078-0432.CCR-12-1904

Santos, M., D’Amico, D., Spadoni, O., Amador-Arjona, A., Stork, O., & Dierssen, M. (2013). Hippocampal hyperexcitability underlies enhanced fear memories in TgNTRK3, a panic disorder mouse model. The Journal of Neuroscience, 33(38), 15259–15271. doi:10.1523/JNEUROSCI.2161-13.2013

Schmidt, M. V, Abraham, W. C., Maroun, M., Stork, O., & Richter-Levin, G. (2013). Stress-induced metaplasticity: from synapses to behavior. Neuroscience, 250, 112–120. doi:10.1016/j.neuroscience.2013.06.059

Teuber, J., Mueller, B., Fukabori, R., Lang, D., Albrecht, A., & Stork, O. (2013). The ubiquitin ligase Praja1 reduces NRAGE expression and inhibits neuronal differentiation of PC12 cells. PloS One, 8(5), e63067. doi:10.1371/journal.pone.0063067

2012

Albrecht, A., & Stork, O. (2012). Are NCAM deficient mice an animal model for schizophrenia? Frontiers in Behavioral Neuroscience, 6, 43. doi:10.3389/fnbeh.2012.00043

Muller, M., Faber-Zuschratter, H., Yanagawa, Y., Stork, O., Schwegler, H., & Linke, R. (2012). Synaptology of ventral CA1 and subiculum projections to the basomedial nucleus of the amygdala in the mouse: relation to GABAergic interneurons. Brain Structure & Function, 217(1), 5–17. doi:10.1007/s00429-011-0326-9

2011

Meis, S., Stork, O., & Munsch, T. (2011). Neuropeptide S-mediated facilitation of synaptic transmission enforces subthreshold theta oscillations within the lateral amygdala. PloS One, 6(3), e18020. doi:10.1371/journal.pone.0018020

2010

Albrecht, A., Bergado-Acosta, J. R., Pape, H.-C., & Stork, O. (2010). Role of the neural cell adhesion molecule (NCAM) in amygdalo-hippocampal interactions and salience determination of contextual fear memory. The International Journal of Neuropsychopharmacology (CINP), 13(5), 661–674. doi:10.1017/S1461145709991106

Rehberg, K., Bergado-Acosta, J. R., Koch, J. C., & Stork, O. (2010). Disruption of fear memory consolidation and reconsolidation by actin filament arrest in the basolateral amygdala. Neurobiology of Learning and Memory, 94(2), 117–126. doi:10.1016/j.nlm.2010.04.007

2009

Janitzky, K., Stork, O., Lux, A., Yanagawa, Y., Schwegler, H., & Linke, R. (2009). Behavioral effects and pattern of brain c-fos mRNA induced by 2,5-dihydro-2,4,5-trimethylthiazoline, a component of fox feces odor in GAD67-GFP knock-in C57BL/6 mice. Behavioural Brain Research, 202(2), 218–224. doi:10.1016/j.bbr.2009.03.038

Sangha, S., Narayanan, R. T., Bergado-Acosta, J. R., Stork, O., Seidenbecher, T., & Pape, H.-C. (2009). Deficiency of the 65 kDa isoform of glutamic acid decarboxylase impairs extinction of cued but not contextual fear memory. The Journal of Neuroscience, 29(50), 15713–15720. doi:10.1523/JNEUROSCI.2620-09.2009

2008

Bergado-Acosta, J. R., Sangha, S., Narayanan, R. T., Obata, K., Pape, H.-C., & Stork, O. (2008). Critical role of the 65-kDa isoform of glutamic acid decarboxylase in consolidation and generalization of Pavlovian fear memory. Learning & Memory (Cold Spring Harbor, N.Y.), 15(3), 163–171. doi:10.1101/lm.705408

Kluge, C., Stoppel, C., Szinyei, C., Stork, O., & Pape, H.-C. (2008). Role of the somatostatin system in contextual fear memory and hippocampal synaptic plasticity. Learning & Memory (Cold Spring Harbor, N.Y.), 15(4), 252–260. doi:10.1101/lm.793008

Meis, S., Bergado-Acosta, J. R., Yanagawa, Y., Obata, K., Stork, O., & Munsch, T. (2008). Identification of a neuropeptide S responsive circuitry shaping amygdala activity via the endopiriform nucleus. PloS One, 3(7), e2695. doi:10.1371/journal.pone.0002695

2007

Narayanan, R. T., Seidenbecher, T., Kluge, C., Bergado, J., Stork, O., & Pape, H.-C. (2007). Dissociated theta phase synchronization in amygdalo- hippocampal circuits during various stages of fear memory. The European Journal of Neuroscience, 25(6), 1823–1831. doi:10.1111/j.1460-9568.2007.05437.x

Narayanan, R. T., Seidenbecher, T., Sangha, S., Stork, O., & Pape, H.-C. (2007). Theta resynchronization during reconsolidation of remote contextual fear memory. Neuroreport, 18(11), 1107–1111. doi:10.1097/WNR.0b013e3282004992

2006

Stoppel, C., Albrecht, A., Pape, H.-C., & Stork, O. (2006). Genes and neurons: molecular insights to fear and anxiety. Genes, Brain, and Behavior, 5 Suppl 2, 34–47. doi:10.1111/j.1601-183X.2006.00229.x

2005

Stork, O. Molekulare Mechanismen der Furchtkonditionierung : molekularbiologische und verhaltensgenetische Untersuchungen amygdalärer Prozesse. 2004, [ca. 200 Bl.] Magdeburg, Univ., Medizin. Fak., Habil.-Schr.,2005

Pape, H.-C., Narayanan, R. T., Smid, J., Stork, O., & Seidenbecher, T. (2005). Theta activity in neurons and networks of the amygdala related to long-term fear memory. Hippocampus, 15(7), 874–880. doi:10.1002/hipo.20120

2004

Stork, O., Zhdanov, A., Kudersky, A., Yoshikawa, T., Obata, K., & Pape, H.-C. (2004). Neuronal functions of the novel serine/threonine kinase Ndr2. The Journal of Biological Chemistry, 279(44), 45773–45781. doi:10.1074/jbc.M403552200

2003

Laxmi, T. R., Stork, O., & Pape, H.-C. (2003). Generalisation of conditioned fear and its behavioural expression in mice. Behavioural Brain Research, 145(1-2), 89–98.

Pape, H.-C., & Stork, O. (2003). Genes and mechanisms in the amygdala involved in the formation of fear memory. Annals of the New York Academy of Sciences, 985, 92–105.

Seidenbecher, T., Laxmi, T. R., Stork, O., & Pape, H.-C. (2003). Amygdalar and hippocampal theta rhythm synchronization during fear memory retrieval. Science (New York, N.Y.), 301(5634), 846–850. doi:10.1126/science.1085818

Stork, O., Yamanaka, H., Stork, S., Kume, N., & Obata, K. (2003). Altered conditioned fear behavior in glutamate decarboxylase 65 null mutant mice. Genes, Brain, and Behavior, 2(2), 65–70.

Szinyei, C., Stork, O., & Pape, H.-C. (2003). Contribution of NR2B subunits to synaptic transmission in amygdaloid interneurons. The Journal of Neuroscience, 23(7), 2549–2556.

Welzl, H., & Stork, O. (2003). Cell adhesion molecules: key players in memory consolidation? News in Physiological Sciences, 18, 147–150.

2002

Stork, O., Ji, F. Y., & Obata, K. (2002). Reduction of extracellular GABA in the mouse amygdala during and following confrontation with a conditioned fear stimulus. Neuroscience Letters, 327(2), 138–142.

Stork, O., Kojima, N., Stork, S., Kume, N., & Obata, K. (2002). Resistance to alcohol withdrawal-induced behaviour in Fyn transgenic mice and its reversal by ifenprodil. Brain Research. Molecular Brain Research, 105(1-2), 126–135.

Stork, O., & Pape, H.-C. (2002). Fear memory and the amygdala: insights from a molecular perspective. Cell and Tissue Research, 310(3), 271–277. doi:10.1007/s00441-002-0656-2

2001

Pape, H. C., Driesang, R. B., Heinbockel, T., Laxmi, T. R., Meis, S., Seidenbecher, T., Szinyei, C., Frey, U., Stork, O. (2001). Cellular processes in the amygdala: gates to emotional memory? Zoology (Jena, Germany), 104(3-4), 232–240. doi:10.1078/0944-2006-00029

Stork, O., Stork, S., Pape, H. C., & Obata, K. (2001). Identification of genes expressed in the amygdala during the formation of fear memory. Learning & Memory (Cold Spring Harbor, N.Y.), 8(4), 209–219. doi:10.1101/lm.39401

2000

Stork, O., Ji, F. Y., Kaneko, K., Stork, S., Yoshinobu, Y., Moriya, T., Shibata, S., Obata, K. (2000). Postnatal development of a GABA deficit and disturbance of neural functions in mice lacking GAD65. Brain Research, 865(1), 45–58.

Stork, O., Welzl, H., Wolfer, D., Schuster, T., Mantei, N., Stork, S., Hoyer, D., Lipp, H., Obata, K., Schachner, M. (2000). Recovery of emotional behaviour in neural cell adhesion molecule (NCAM) null mutant mice through transgenic expression of NCAM180. The European Journal of Neuroscience, 12(9), 3291–3306.

1999

Stork, O., & Welzl, H. (1999). Memory formation and the regulation of gene expression. Cellular and Molecular Life Sciences, 55(4), 575–592.

Stork, O., Welzl, H., Wotjak, C. T., Hoyer, D., Delling, M., Cremer, H., & Schachner, M. (1999). Anxiety and increased 5-HT1A receptor response in NCAM null mutant mice. Journal of Neurobiology, 40(3), 343–355.

1997

Stork, O., Welzl, H., Cremer, H., & Schachner, M. (1997). Increased intermale aggression and neuroendocrine response in mice deficient for the neural cell adhesion molecule (NCAM). The European Journal of Neuroscience, 9(6), 1117–1125.

1994

Stork, O., Hashimoto, T., & Obata, K. (1994a). Haloperidol activates tyrosine hydroxylase gene-expression in the rat substantia nigra, pars reticulata. Brain Research, 633(1-2), 213–222.

Stork, O., Hashimoto, T., & Obata, K. (1994b). Increase of tyrosine hydroxylase and its mRNA in the rat substantia nigra pars reticulata by diazepam and picrotoxin. Neuroscience Research, 19(1), 73–80.