Yunus Emre Demiray, M.Sc.

YunusI am a postdoctoral researcher since August-2021 in our group. My research deals with signalling cascades that are important during neuronal development. I use molecular and pharmacological tools on primary neuronal cultures to analyse morphology and protein biochemistry. In my current project, I study how integrin receptors and its downstream cytoskeleton elements interact and control dendritic growth. Furthermore, by combining viral interventions with behavioral characterization, I will focus on how such structural changes on dendrites can translate to physiological and behavioural modulations in vivo.

Education
B.Sc. in Molecular Biology and Genetics, Bilkent University, Ankara, Turkey 2012

M.Sc. in Integrative Neuroscience, Otto-von-Guericke University, Magdeburg, Germany 2015

Phd in Neurobiology, Otto-von-Guericke-University, Magdeburg, Germany 2021

Contact information
E-mail: yunus.demiray[at]st.ovgu.de
Telephone: +49(391)-67 55119

Publications

Caliskan G, Demiray YE, Stork O. Comparison of three common inbred mouse strains reveals substantial differences in hippocampal GABAergic interneuron populations and in vitro network oscillations. Authorea. November 17, 2022.
Madencioglu DA, Çalışkan G, Yuanxiang P, Rehberg K, Demiray YE, Kul E, Engler A, Hayani H, Bergado-Acosta JR, Kummer A, Müller I. Transgenic modeling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function. iScience. 2021 Aug 20;24(8):102868.
 

Tripathi K, Demiray YE, Kliche S, Liang J, Hazra S, Hazra JD, Richter-Levin G, Stork O. Reducing glutamic acid decarboxylase in the dorsal dentate gyrus attenuates juvenile stress induced emotional and cognitive deficits. Neurobiology of stress. 2021 Jun 2:100350.

Regev Tsur S, Demiray YE, Tripathi K, Stork O, Richter-Levin G, Albrecht A. Region-specific involvement of interneuron subpopulations in trauma-related pathology and resilience. Neurobiology of Disease 2020; 143:104974. 

Çalışkan G, Raza SA, Demiray YE, Kul E, Sandhu KV, Stork O. Depletion of dietary phytoestrogens reduces hippocampal plasticity and contextual fear memory stability in adult male mouse. Nutritonal Neuroscience 2019, Epub ahead of print Dec 9:1-12. 

Waldt N, Seifert A, Demiray YE, Devroe E, Turk BE, Reichardt P, Mix C,Reinhold A, Freund C, Müller AJ, Schraven B, Stork O, Kliche S. Filamin A Phosphorylation at Serine 2152 by the Serine/Threonine Kinase Ndr2 Controls TCR-Induced LFA-1 Activation in T Cells. Front Immunol. 2018 9:2852

Sandhu KV, Demiray YE, Yanagawa Y, Stork O. Dietary phytoestrogens modulate aggression and activity in social behavior circuits of male mice. Hormones and Behavior 2020, 26:104637. doi: 10.1016/j.yhbeh.2019.104637.

Demiray YE, Rehberg K, Kliche S, Stork O. Ndr2 kinase controls neurite outgrowth and dendritic branching through alpha1 integrin expression. Front. Mol. Neurosci. 2018; 11:66.

Raza SA, Albrecht A, Çalışkan G, Müller B, Demiray YE, Ludewig S, Meis S, Faber N, Hartig R, Schraven B, Lessmann V, Schwegler H, Stork O. HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience. Nat Commun. 2017 Aug; 8(1):189.

DFG Research Training Group 2413 SynAGE