I re-joined the lab in 2019 after a postdoc abroad. I am interested in the integration of different contradictory cues, for example cues signalling a threat and cues signalling the non-occurrence of a threat. My current project deals with the anatomical basis of the divergent and convergent processing of these cues. To this end, I use immunohistochemistry to correlate brain activation patterns with successful behavioral integration and the TetTag mouse to simultaneously label neurons that are activated by either one or both cues.
Education
Undergraduate studies in Psychology, University of Vienna, Austria 2006
Diploma in Neuroscience, Otto-von-Guericke University, Magdeburg, Germany 2010
PhD in Neuroscience, Otto-von-Guericke University, Magdeburg, Germany 2015
Postdoc, Otto-von-Guericke University, Magdeburg, Germany 2015-2016
Postdoc, Purdue University, USA 2017-2019 (Feodor Lynen Program)
Postdoc, Otto-von-Guericke University, Magdeburg, Germany since Sept.2019 (Feodor Lynen Program)
Contact information
E-mail: irismueller1985[at]gmail.com
Telephone: +49(391)-67 55108
Publications
Müller I, Brinkman AL, Sowinski EM, Sangha S. (2018) Adolescent conditioning affects rate of adult fear, safety and reward learning during discriminative conditioning. Sci Rep 8(1):17315.
Colic L, Li M, Demenescu LR, Li S, Müller I, Richter A, Behnisch G, Seidenbecher CI, Speck O, Schott BH, Stork O, Walter M. (2018) GAD65 promoter polymorphism rs2236418 modulates harm avoidance in women via inhibition/excitation balance in the rostral ACC. J Neurosci 38(22):5067-5077.
Albrecht A, Müller I, Ardi Z, Caliskan G, Gruber D, Ivens S, Segal M, Behr J, Heinemann U, Stork O, Richter-Levin G. (2017) Neurobiological consequences of juvenile stress: A GABAergic perspective on risk and resilience. Neurosci Biobehav Rev 74(Pt A):21-43.
Caliskan G, Müller I*, Semtner M, Winkelmann A, Raza AS, Hollnagel JO, Rösler A, Heinemann U, Stork O, Meier JC. (2016) Identification of Parvalbumin Interneurons as Cellular Substrate of Fear Memory Persistence. Cerebral Cortex 26(5):2325-40
Müller I, Caliskan, G, Stork O. (2015) The GAD65 knock out mouse – a model for GABAergic processes in fear- and stress-induced psychopathology. Genes Brain Behav 14(1): 37-45.
Müller I, Obata K, Richter-Levin G, Stork O. (2014) GAD65 haplodeficiency conveys resilience in animal models of stress-induced psychopathology. Front Behav Neurosci 8:265
Bergado-Acosta JR, Müller I*, Richter-Levin G, Stork O. (2014) The GABA-synthetic enzyme GAD65 controls circadian activation of conditioned fear pathways. Behav Brain Res 260:92-100.
Li K, Müller I, Patil S, Höger H, Pollak A, Russo-Schlaff N, Lubec G, Li L. (2012) Strain-independent global effect of hippocampal proteins in mice trained in the Morris water maze. Amino Acids 43(4):1739-49.
*equal contribution