My research encompasses behavioral and biochemical approaches to investigate progression and intervention time-windows of the phenotypes and the pathology associated with mouse models of neurodegenerative diseases. Ultimately, my aim is to develop novel strategies for prevention or rescue of these phenotypes. To this end, I use genetic anti-sense approaches, as well as drugs that target various pathways that are known to play important modulatory roles in neurodegeneration. I make use of stereotaxy and various drug delivery systems to achieve accurate and timely delivery of these substances that can potentially alleviate neurodegeneration.
B.Sc. in Chemistry, Bilkent University, Ankara, Turkey 2010
M.Sc. in International Economics & Finance, Otto-von-Guericke University, Magdeburg, Germany 2014
PhD in Neurobiology, Otto-von-Guericke University, Magdeburg, Germany 2020
Telephone: +49(391)-67 55119
Martínez-Rodríguez E, Martín-Sánchez A, Kul E, Bose A, Martínez-Martínez FJ, Stork O, Martínez-García F, Lanuza E, Santos M, Agustín-Pavón C. Male-specific features are reduced in Mecp2-null mice: analyses of vasopressinergic innervation, pheromone production and social behaviour. Brain Struct Funct. 2020. Epub ahead of print. doi: 10.1007/s00429-020-02122-6.
Martínez-Rodríguez E, Martín-Sánchez A, Coviello S, Foiani C, Kul E, Stork O, Martínez-García F, Nacher J, Lanuza E, Santos M, Agustín-Pavón C. Lack of MeCP2 leads to region-specific increase of doublecortin in the olfactory system. Brain Struct Funct. 2019; 224(4):1647-1658
Castro H, Kul E, Buijsen RAM, Severijnen LWFM, Willemsen R, Hukema RK, Stork O, Santos M. Selective rescue of heightened anxiety but not gait ataxia in a premutation 90CGG mouse model of Fragile X-associated tremor/ataxia syndrome. Hum Mol Genet. 2017 Jun ;26(11):2133-2145.